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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

C罗巨无霸般的收入主要来源于两部分。一部分是他效力于西班牙豪门皇家马德里挣得的令人眼红的3850万英镑的年薪。另一部分来源于他为耐克、豪雅表和营养品公司康宝莱代言带来的总计2200万英镑的代言费。
报告指出,中国网游开发商自今年年初以来一直在考虑按照时间收费。在排名前十的网络游戏中,时间收费型网游占据了4个席位,其中两款是今年才开始商业化运营的新游戏,包括盛大互动娱乐有限公司(Shanda Interactive Entertainment)的主要新游戏《永恒之塔》(AION)。Cnzz.com说,转向时间收费模式更有可能给游戏带来公平和公正感,因为玩的最好的玩家将是那些花时间最多的人,而不是那些花钱最多的用户。

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
From the themed collection: 绿色建材发展即将驶入“快车道”
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

Best of luck in the year to come.愿你在未来的一年里,吉星高照。
Will the Democrats take back the majority in the midterm election in the US House of Representatives

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

本麦克兰纳汗(Ben McLannahan)是美国银行业编辑

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

此外,该报告还指出,雨果博斯、雪佛兰和舒洁则跌出了该榜单。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

v. 劳累,拉紧,过份
Female and male participants typically have similar profiles at the start of their EMBA.
"People can be unhappy for many reasons -- from poverty to unemployment to family breakdown to physical illness," the report said. "But in any particular society, chronic mental illness is a highly influential cause of misery. If we want a happier world, we need a completely new deal on mental health."
n. 代表,副手

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

But that kind of emotional identification gets lost on the runway, and the retail floor. And then we are left with what?
“We weren’t looking to throw the bums out, as they might say about an election. We were just really impressed with a flood of new powertrains, ” says Drew Winter, WardsAuto World Editor-in-Chief. “What was great yesterday might be less impressive tomorrow because engine technology is changing so rapidly.”
《阳光小美女》的夫妻档幕后团队将1977年鲍比.里格斯和比利.简.金之间的性别大战拍成了电影。55岁的里格斯是职业网球运动员,他向年轻的王牌选手简.金(当时世界排名第二)发起挑战赛,结果落败。
8.出租车司机

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

China's employment situation is generally stable in the first quarter of 2016, said Li Zhong, Spokesman of the Ministry, adding that the economic downturn and structural reform, however, make employment more difficult.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
From the themed collection: 五年内我国水性涂料占比或可达20%
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

Wang Dengfeng, director of the Physical Education, Health and Art Department under the Ministry of Education (MOE) and Vice Chairman of the China Football Association, was quoted as saying that football experts are designing curriculums for more than 360 training programs in primary and secondary schools.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

adj.
In the wake of the Fitbit and Google’s GOOG 0.26% Glass, a flurry of companies has flooded the market with iterations of sensor-laden armbands, apparel, and eyewear. It’s a buzzy category, but early adopters seem to be waiting for a moment when they are no longerthat guy. (You know. The “Glasshole.”)

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

inspection
单词trademark 联想记忆:

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
From the themed collection: 长租品牌公寓成为租客新宠
Open Access Review Article

Diagnostic technologies for COVID-19: a review

But it's the best pay on offer for a major world leader.
We will ensure that foreign trade continues to pick up and register steady growth.

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

Scott Brooks gets leeway as he learns his roster, and injuries continue to play too big a role. But I just can't fathom why this team is so much worse than the playoff team from a couple years back. The other piece is that it's unlikely the Wizards can conceivably be bad enough to get a top-five pick.
Song “The Spring Blossom” (Na Ying)
这位工作人员表示:“我们的数据显示该用户的年龄是28岁,并非媒体上报道的13岁。”
近日公布的一份调查结果显示,清华大学毕业生的平均薪酬在全国高校毕业生中最高。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

另一方面,2月PPI同比下降4.9%,低于1月5.3%的同比降幅。2月PPI降幅为8个月以来最低降幅。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

在一份电邮声明中,国际足联表示,在小组赛中,三等票总计售出143364张,相当于每场比赛就卖出了3000张。
With an 8.5-percent increase in profits, industrial enterprises reversed the previous year's negative growth of 2.3 percent.

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

A happy New Year to you.

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
From the themed collection: 智能家居落地还有多远?
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

Its GDP increased 7.5 percent compared to last year, according to a report by 21st Century Business Herald.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

New Year time is here. I hope you have a wonderful New Year. May every day hold happy hours for you.新年来临,祝新年快乐,愿你时时刻刻幸福欢乐!
'She enjoys it and we don't force her to do anything she doesn't want to do.'
9. Investors brains are so distracted, in denial, they won't get out in time.
我去年就说过、今年要再强调的一点是:唯一比预测未来更不招人待见的事情就是公开自己的预言。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

随着他不断运用网络来搜集知识,达洛伊西奥意识到,他急需一个能让他快速确定文章阅读价值的方法。于是他构想了一个摘要工具,能运用语言学理论来编写低于400字的内容提要。
In my anger, I am not blind, and in my fear, I am not afraid to tell the world how I feel. 然而事实却让我很愤怒,但我也很清醒,我虽然害怕,但我敢于告诉世界我真实的感受。
Effective bosses and managers tend to:
Leila Janah
该研究基于数亿个安全问题的答案以及数百万条恢复账号登录的请求。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

英国国家卫生署去年公布的入院患者的数据显示,各种各样的营养性疾病和传染性疾病在过去十年来以惊人的速度增长着。
A lack of capital and experience is the biggest obstacle for college entrepreneurs, the report suggested, stating that 40 percent of such young entrepreneurs rely on external capital such as loans from banks, investment organizations, schools and the government.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

7.狱警

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

摩洛克位于非洲北部地区,被称为通往非洲的一扇大门,主要旅游城市包括首都拉巴特、最大城市卡萨布兰卡、马拉喀什以及阿加迪尔市。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

cast
5. Repeats & highlights are as good as the main match, so am gonna watch them.
2.Yeah, I’ll start working on that ASAP! – Because telling you I have 10 things to do first would just irritate you。
从事房地产业的中国女富豪最多,占23%,金融投资业占18%,制造业占14%。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

popul人民+ar…的→流行的
周四,胡润研究院发布了品牌榜单,估价447亿美元的腾讯成为今年最有价值的中国品牌,这是腾讯连续第二次位居榜首了。
谎言9:对,我在高中足球队里就是个捣蛋鬼!说谎原因:我想让自己在别人的眼里更加闪亮。
据BusinessInsider.com报道,麦嘉华夸张地说,“QE基本上会成为我们下半辈子日常生活的一部分”。麦嘉华还说,2010年在贝南克灾难性试验的早期阶段,他曾给出“美联储奔向QE99”的警告。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

The drop was even more pronounced measured in US dollars, with exports crashing 11.2 per cent year-on-year last month to $177.48bn. That was from a 1.4 per cent drop in December, and versus expectations for a 1.8 per cent slide. It was the biggest drop since a 15 per cent fall in March last year.
尽管有少数人坚持这种说法,但绝大多数研究气候的科学家表示,地球正在经历一个长期变暖的趋势,这种趋势给人类带来深刻的威胁,而且几乎完全是由人类活动造成的。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

2014年出现了这么多大有前途的新剧:《真探》(True Detective)、《荣耀之女》(The Honorable Woman)、《冰血暴》(Fargo)、《婚外情》(The Affair)、《奥丽芙·基特里奇》(Olive Kitteridge)和《硅谷》(Silicon Valley)等。有些老剧仍在坚持,或者莫名其妙地重振雄风,或者在被砍后再次回归,最显眼的是丽莎·库卓(Lisa Kudrow)主演的HBO喜剧《归来记》(The Comeback),它在2005年播出一季后被砍,今年11月回归。
商务部本月早些时候表示,消费品的零售销售是去年消费的一项关键指标。该销售额同比增长了10.7%,占去年全国66.4%的GDP增长。
adj. 已被确认的,确定的,建立的,制定的 动词est
The World Health Organization this year declared H1N1 a global epidemic. Fortunately, it is much less threatening than people previously believed, and newly introduced vaccines seem to have quelled lingering fears.
其中包括“qwerty”(键盘字母顺序,排名第4)、“admin”(管理员,排名第11)和“login”(登录,排名第14)。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

2.德语:增长了22.2%
10月份,美国联邦政府停止运转。星巴克CEO霍华德舒尔茨拒绝在所有公司都受到不利影响时袖手旁观。他写了一封请愿书,号召各公司CEO上街游行,给国会施加压力,迫使后者通过预算案。
从全国来看,上个月70个主要城市中62个城市的房价环比上涨,1个城市房价不变,还有7个城市出现下跌。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

Christie’s biannual evening sale on Dec. 8 raised just 6.5 million pounds with fees, about $9.7 million, against a low estimate of 12.7 million. Nineteen of the 45 works, or 42 percent, failed to sell, including the two most highly valued lots — a 1582 watercolor study of a hare among plants by Hans Hoffmann, a pupil of Albrecht Dürer, and a fine 1770s Francesco Guardi view of the island of San Giorgio Maggiore in Venice, carrying low estimates of 4 million and 1.5 million respectively.
China is committed to denuclearization of the Korean Peninsula, the peace and stability in the Korean Peninsula, and resolving issues through dialogue and consultation. That is China’s consistent and clear-cut position.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

Lana Del Rey, 'Lust for Life'
She added that because of economic conditions and anti-immigration sentiment in some Western countries, many Chinese students find it difficult to stay in those countries.
德银资产管理公司(Deutsche AM)亚太区被动型资产管理部门主管马尔科?蒙塔纳里(Marco Montanari)也认为,在亚洲ETF市场迈向更高台阶之前,必须从根本上改革分销制度。

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
From the themed collection: 2015淋浴房十大品牌最新排行榜
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

北京首都国际机场的情况稍好一些,其准点率达60.7%。
“有个人给同事发了条短信说自己辞职了,并请她把这条短信转发给高管。”
We learned about a warehouse that is like a mausoleum for endangered species.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

The gold market may be obsessed about the dollar and prospect of a rise in US interest rates. But there’s another factor looming on the horizon: a fall in gold mine supply.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

8Australia

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
From the themed collection: 佛山市成立首个情调照明联盟
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

Best chances: Best film, and best original screenplay recognition looks certain, and Frances McDormand is currently the favorite for the best actress Oscar.
玛戈特·瓦尔斯特伦(Margot Wallstrom)

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

1. World Health Organisation declares a public emergency of international concern over Zika
The Harvard article suggests that protecting the brain with a heart-healthy diet could be the key to warding off dementia and keeping your memory intact well into your golden years. Some studies have suggested certain foods have a positive impact on memory, but no study thus far has revealed the existence of a miracle food. The idea that a heart-healthy diet could also prove beneficial to the brain and memory has become popular with doctors studying Alzheimer's disease and dementia. Some of the risk factors associated with heart disease are similar to those associated with dementia and Alzheimer's. Foods recommended for a heart-healthy diet include fruits, vegetables, and whole-grain bread, as well as beans, nuts, and olive oil. If you can't use every one of these 10 scientific secrets to a perfect memory, a healthy diet might help you avoid losing it!
“Today you have to shop by image,” Mr. Nathan said. “But if you are brave and don’t follow fashion, there are opportunities.”
vt. 编预算,为 ... 做预算

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

“This growth is further backed by Video Editing making an appearance at number 3 on the list with a 19% increase,” the report states, “as video content becomes one of the initial draws and call to actions for most customer-focused websites. Heavy video marketing through social media also increases this demand.”
今年最佳的季中交易早已发生了:

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

China denies any wrongdoing and says it is working to tackle problems of industrial overcapacity that have become more acute as its economy has slowed.
4. Stop eating, gotta get those cheekbone sharp enough to cut butter.

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

Will the S&P 500 finish the year above 2,650

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

['traigl]
Judge for yourself.
《财富》美国500强公司苹果(Apple))已宣布,将从现金中拿出300亿美元用于股票回购。这个消息让投资者很高兴:股价暴涨,甚至在消息发布一周后,这只股票相对于标准普尔指数在这7天上涨了12%。苹果有一项规模更大、总额高达1300亿美元的资本回报计划,将一直延续到2015年,而这些回购就是这项计划的一部分。
在NBA,很少人能防得住罗斯。那么,你可以想象,在罗斯的高中年代,有着和现在一样的NBA身板,要防住他更是天方夜谭。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

节目11 歌曲《我心永恒》,席琳-迪翁
Meanwhile, producer prices were deflating at a rate of -5.9 per cent, a six-year low, for a third straight month.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

担忧、紧张、抑郁和愤怒等负面情绪更常在D型人格的人身上体现。一件常常被他人忽视的小事就可能让D型人格的人烦恼,甚至会破坏他的心情。
5. How to play poker
让自己坐的舒适。在弄了这么多之后,最重要的一点是要让自己感觉到很舒适。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

最佳女歌手:米兰达·兰伯特
目前全国11个省的52所高校配备了自动售货机,出售艾滋病检测试剂以供学生自查。
积极稳妥去杠杆。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

昨日,108名表演者身着熊猫服装,穿行在伦敦的街头,向大众宣传这种惹人喜爱却面临灭绝危险的黑白物种。
《少年收容所》(Short Term 12)是独立制片的小型影片之一,然而却会大大地影响观众。这部低成本电影片长仅96分钟,背景是一个针对问题青少年的收容设施。然而德斯汀?克里顿(Destin Cretton)的导演和布里?拉尔森(Brie Larson)的表演让这部电影跻身年度最佳影片之列。拉尔森几乎可以肯定无缘奥斯卡奖(今年的竞争异常激烈),但她对所扮演的女主角格蕾丝(Grace)的刻画极具水准,格蕾丝是一名20多岁的年轻保育员,她自己的生活远非平静无波。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

adj. 暴露的,无掩蔽的,暴露于风雨中的 v. 暴露,
会,即便真实的GDP增速未超过这个数字。关于中国真正的(相对官方数据而言)GDP增长率的猜测,已经衍生出一个由相关经济学专家组成的作坊式行业。官方数据看似稳定而美好——有人怀疑中国有关部门对数据进行了“美化”,调整了一些数字、使其符合增长目标。因此,即使2018年中国的增长磕磕绊绊,官方的增速也几乎肯定会高于预定的6.5%。
The King’s Woman

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
From the themed collection: 分析:佛山8月建材价格持续下滑
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

“有个人给老板发了个短信,说他要离职了。”
在成为德国最大贸易伙伴之前,中国是德国在亚洲的最大贸易市场。在过去两年里,德国一直是中国在欧洲最大的贸易伙伴。

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

世界知识产权组织总干事弗朗西斯·居里表示:“投资创新是提高长期经济增长的关键。在当前的经济形势下,发现新的增长来源并利用全球创新所带来的机会是所有利益相关者的优先事项。”
Plum Alley:
No. This is possible, of course, but with luck, Mrs May has at least now ensured that the UK is not going to tumble over a “no deal” cliff in 2019. In December 2017, Consensus Forecasts’ prediction for the UK was of 1.5 per cent growth in 2018. Its forecasts for Japan and Italy were even lower, at 1.3 per cent. So the chances that the UK will have the slowest-growing economy in the G7 next year should be around one in four.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

3、美酒佳人。 邦德走到哪里喝到哪里,美酒的确能帮他俘获佳人。喜欢喝一杯的人最容易在第一次约会时就抱得美人归。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

adj. 傲慢的,自大的
For: The National Board of Review gave it their best film, actor and actress awards.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

● “奥巴马总统证实,如果特朗普当选他将拒绝离开白宫”
《大白鲨》的故事非常不现实,但它的原型是1916年由一条鲨鱼造成的一系列真实命案。在被称为“史无前例的系列鲨鱼袭击事件”中,2周内,泽西海岸边有4人被鲨鱼咬死。据报道,犯案的鲨鱼被捕后,消化道中还有尸骸。不过,权威科学家至今无法确定,是什么驱使这条鲨鱼袭击了这么多人。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

单词spontaneous 联想记忆:
“Nick is an exceptional product thinker,” Adam Cahan, Yahoo’s senior vice-president of mobile and emerging products, said. “He does represent a generational shift in the kinds of things he is thinking about and what it means to be truly mobile. That generation is not just mobile-first, they are mobile only. That’s a different point of view.”

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

AR could be the bigger opportunity after Apple’s Tim Cook gave the technology his backing — it was included in Apple’s latest operating system and its iPhone X device.
尽管当下是一个全球性的经济环境,但仅有约20%的美国人会说第二门语言。Sixty Vocab的目标就是以其在线外语游戏改变这一现状。基于2000个单词相当于一门外语的六成精髓的假设,Sixty Vocab试图使学习必要词汇的过程变得有趣。这些在线游戏能教你在对话中最为常用的词汇,并辅以限制时间的规则——你在越短的时间内猜出单词,你就能越快地进入到下一个阶段。Sixty Vocab填补了你高中课程和昂贵外语学习项目之间的空白,为那些想要在早餐咖啡或通勤时间学习一门外语的人提供了一个独一无二的选择。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

associate

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

Whedon had always loved the seemingly separate ideas of sci-fi and westerns, and through The Killer Angels, he saw a way to combine them. "I wanted to play with that classic notion of the frontier," he said. "Not the people who made history, but the people history stepped on—the people for whom every act is the creation of civilization." And Whedon decided to set the frontier on a spaceship: a ship named Serenity.
In contrast, the average unit price of emerging market exports has been falling in year-on-year terms pretty much since mid-2012, hitting a year-on-year decline of 16.4 per cent in February 2016.
The company is hardly alone in its efforts to woo talent of a different sort. Earlier this year Intel announced a collaboration with the Council of Fashion Designers of America, or CFDA, kicking off a partnership with the high-concept retailer Opening Ceremony to design its smart bracelet. Tory Burch partnered with Fitbit to design pendants and bracelets akin to the Shine Tracker by Misfit Wearables. And Apple AAPL -1.03% has tapped a diverse group of people, including former Burberry chief executive Angela Ahrendts (to lead its retail efforts), former Yves Saint Laurent CEO Paul Deneve, and former Nike NKE -0.71% design director Ben Shaffer.
律师本质上是谨慎的,但他们中的大多数人已经认识到,技术是处理他们需要梳理的大量信息的关键。没有技术,披露和合规等一些需要处理很多文件的工作几乎不可能完成。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
From the themed collection: 谋求突破 家居企业“扎堆”IPO
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

一次投入全部很少能够成功。虽然确实有人倾其所有,在六个月或一两年之后成为赢家,但这只是个案。对于任何初创公司来说,风险管理都是一个重要元素,账目平衡至关重要。如果你在最开始承担的风险更少,你就更容易消化损失。而这些损失将是必不可少的、富有价值的教训。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

她的母亲,32岁的史蒂芬妮·博伊登称,波比非常有主角意识,听到别人叫她上台就会兴奋的跑过去,让她下台的时候就会愤怒的尖叫。
Lawrence’s 2016 earnings dropped 11.5 percent from her 2015 total of $52 million. Forbes will release its list of the world’s highest-paid actors on Thursday. Last year Robert Downey Jr. topped the list with an estimated $80 million.
But that hasn't stopped scientists from growing actual human brains in a lab. Starting with nothing but stem cells, scientists in Austria this year managed to create brains equivalent to those in nine-week-old fetuses. These miniature brains are the size of peas and are incapable of thought—so far. The one thing keeping the brains from growing beyond this stage and becoming fully functional is that they have no blood supply.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

"Although it may seem counterintuitive, the best way to maximize profits over the long-term is not to make them the primary goal of the business," Mackey said in an interview earlier this year.
designated

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

I am calling this the Wan Long prize, after the Chinese meat magnate who once uttered the clearest sentence ever spoken by a CEO: “What I do is kill pigs and sell meat.” Mr Wan will surely approve of my winner, a BNSF railway executive who told a conference: “We move stuff from one place to another.”
Hope all your New Year dreams come true!

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

She had recently emerged as the right hand of her father, the former Prime Minister Nawaz Sharif. But corruption charges are clouding her rapid rise.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
From the themed collection: 深圳:坚持不懈保障和改善民生
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

Against: Could the film be seen as a film of great performances, rather than a truly great piece of cinema
单词transportation 联想记忆:
“授课的是一流从业者,”该学院一名毕业生表示,“该项目为只有极少金融业工作经验的年轻专业人士量身打造,学生们毕业后马上就能投入工作。”

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

The unemployment rate probably won't fall quite as rapidly in 2015, according to economists, especially if more people enter the labor force because jobs are easier to find. Yet another large spate of hiring similar to the gain in 2014 would make the low unemployment rate more believable.
n. 安装,放置,周围,环境,(为诗等谱写的)乐曲
南韩的活动分子在星期二发誓,要在月底通过宣传气球跨越边境向北韩偷运荷里活讽刺片"刺杀金正恩",以作为对北韩不断威胁的反抗。
demo人民+-ic…的]→人口统计的

Graphical abstract: Length-scale dependence of protein hydration-shell density
From the themed collection: 前2月一线土地出让增84%
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

['benifit]
When you need help, reach out to people in your networks – that’s what they’re there for. Whether you need a confidence-boosting pep talk or advice about building your technical experience — your mentor, your colleagues, and your manager can help. You may not know how to do something today, but chances are you’re smart enough to find someone who can help you learn it. And once you do, don’t unfasten your seatbelt – there’s always going to be another challenge headed your way.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
From the themed collection: “人情味”营销模式走红家具行业
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

陶博宏表示,这可能过于悲观了。他说:“亚洲的情况往往比我们想象的更快变化。”
['k?:p?rit]
Exports declined 6.9 per cent in October from a year earlier, deteriorating from the 3.7 per cent fall the previous month as weak global demand and higher Chinese costs led to slumping shipments of the cheap Chinese goods that have flowed to the world in the last decade.

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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您只需把杯子放到啤酒机上,杯底磁铁就会自动抬高,让啤酒流进杯子里。
自从美国的民权运动以及欧洲敞开国界以来,多元文化主义已经兴盛数十载,这些问题似乎是一种突然的逆转。

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